The PROP1 2-Base Pair Deletion Is a Common Cause of Combined Pituitary Hormone Deficiency
نویسندگان
چکیده
منابع مشابه
PROP1 gene analysis in Portuguese patients with combined pituitary hormone deficiency.
OBJECTIVE Mutations of the PROP1 gene lead to combined pituitary hormone deficiency (CPHD), which is characterized by a deficiency of GH, TSH, LH/FSH, PRL and, less frequently, ACTH. This study was undertaken to investigate the molecular defect in a cohort of patients with CPHD. DESIGN, PATIENTS AND MEASUREMENTS A multicentric study involving 46 cases of CPHD (17 familial cases belonging to s...
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ژورنال
عنوان ژورنال: Journal of Clinical Endocrinology & Metabolism
سال: 1998
ISSN: 0021-972X
DOI: 10.1210/jc.83.9.3346